Key takeaways
- The Rejuran range consists of four distinct variants; Rejuran Healer, Rejuran i, Rejuran s, and Rejuran HB+. Each is intended for a specific treatment area or skin concern in mind, rather than being a one-size-fits-all option.
- Choosing the most appropriate variant is a personalised clinical decision based on factors such as the treatment area, your skin condition, and your overall health. It isn’t something that can be decided through online research or personal preference alone.
- In some cases, a combination approach may be discussed as part of a broader treatment plan. A consultation with a qualified medical professional is an essential first step before any treatment is considered.
If you have been researching Rejuran treatments in Melbourne, you’re probably wondering which one is right for you.
Because it’s designed to work with the skin’s own biology, the “best” version of the treatment is entirely dependent on the specific area being addressed and the individual skin concerns involved.
Rather than a single universal product, the Rejuran range includes several variants, each developed with a different concentration and texture suited to different treatment areas and concerns.
In this post, we’ll break down the differences between the variants to outline how a medical professional determines which one may be most appropriate as part of an individualised treatment plan.
Understanding the Rejuran range
Rejuran is a bio-regenerative treatment built around polynucleotides, which are DNA fragments sourced from salmon and are considered biocompatible with the skin. This foundation is consistent across the entire range. What differs between variants is the concentration, texture, and formulation, each developed for specific treatment areas or skin concerns.
Understanding this foundation is key to how this treatment works, particularly in how polynucleotides interact with the skin at a cellular level
Choosing between Rejuran variants is not simply a matter of personal preference. It is a clinical decision based on the area being treated, the skin concerns involved, and individual factors assessed during a consultation. This includes not only the treatment itself but also how Rejuran aftercare may be managed following each session
A medical professional determines which variant may be suitable for you based on that assessment rather than a general recommendation.
Understanding the differences between them is a useful starting point, but it is not a substitute for professional guidance. What follows is an overview of the variants currently available and the contexts in which each one is most commonly discussed.
Rejuran i
Rejuran i is the variant formulated for use in the delicate skin around the eye area. The “i” references the periorbital region, and the formulation reflects the specific needs of that treatment zone. The skin around the eyes is considerably thinner and more sensitive than elsewhere on the face, which means a standard formulation would not be appropriate for use in that area.
The concentration and texture of Rejuran i have been adjusted for this delicate environment. It is designed to be administered with precision into the treatment zone, requiring a gentler approach than broader facial treatment areas.
Concerns often raised in discussions of Rejuran i include fine lines around the eye area, loss of firmness, and a tired or dull appearance. It is also sometimes discussed alongside full face treatments as a complementary focus area, rather than a standalone option.
As with all variants in the Rejuran range, suitability for Rejuran i is determined during a personalised consultation with a qualified practitioner. Whether it may be appropriate for individual concerns and anatomy is a decision made by your medical professional, rather than one that can be made through general research alone.
Rejuran s
Rejuran s is the variant formulated with a focus on scarring and textural irregularities. The “s” reflects this specific application, and the formulation differs from other variants in the range for use in skin affected by scarring, most commonly in the context of acne scarring.
Acne scarring presents a different set of challenges to general skin quality concerns. The skin’s texture and surface integrity can be significantly disrupted, and addressing that may involve formulations intended to support the skin’s natural repair processes at a deeper level. Rejuran s is formulated with this context in mind.
It is worth noting that not all scarring will be considered appropriate for this treatment, and the degree to which Rejuran s may be associated with changes in the appearance of scarring can vary considerably between individuals. Outcomes are not guaranteed, and the condition of the scarring, its depth, and the overall skin profile will all form part of the clinical assessment.
A personalised consultation with a qualified medical professional is required to determine whether Rejuran s may be relevant to your specific concerns and whether it is clinically suitable for your skin.
Rejuran for full face and neck
For broader treatment areas, two variants are often discussed. Rejuran Healer and Rejuran HB+. Both share the same polynucleotide foundation as the rest of the range but are formulated for use across larger treatment areas across the face and neck.
Rejuran Healer is the standard formulation used in broader treatment areas. It is designed to help support overall skin quality across a broader treatment zone, in the context of concerns such as dullness, dehydration, uneven texture, and the early signs of fine lines and wrinkles across the face and neck as a whole, rather than targeting a specific area.
Rejuran HB+ combines polynucleotides with hyaluronic acid. A key distinction of the HB+ variant is its focus on the treatment experience. It has been formulated with consideration for comfort during the administration process, making it a consideration for those who may value a smoother clinical session. The addition of hyaluronic acid is associated with increased hydration, which is why this variant may be discussed in relation to particularly dehydrated or compromised skin.
Which of these two variants may be appropriate is not a decision that can be made without a proper clinical assessment. The choice between Rejuran Healer and Rejuran HB+ will depend on your individual skin profile, concerns, and the treatment plan developed during your consultation with a qualified medical professional.
Professional standards at Luxe Lips
At Luxe Lips, a cosmetic clinic in Melbourne, our care is grounded in medical ethics and a focus on clinical responsibility. Every treatment pathway is approached as a medical process, with established health protocols and safety guiding each step.
Across our clinics in Moonee Ponds, Camberwell, and Brighton, our medical professionals carry out a thorough screening process for every person. This includes reviewing medical history, assessing anatomical suitability, and considering psychological readiness. In line with local guidelines, this evaluation helps determine whether a proposed plan aligns with your health.
Practitioners proceed only when a treatment is clinically appropriate. If a procedure does not align with your anatomy or health profile, we will explain why and discuss what that means for you. The focus is always on clear information and maintaining a clinical environment where safety and ethical standards come first.
Because responses and circumstances vary, booking an aesthetic consultation is required to determine suitability before Rejuran treatment is considered.
Note: Individual responses vary. A consultation with a qualified professional is required to determine the suitability of any treatment for your specific needs.
Questions we’re often asked about which Rejuran is best
The Rejuran range currently includes four variants, each developed with a specific treatment area or skin concern in mind. Rejuran Healer is the standard formulation used for broader treatment areas such as the full face and neck.
Rejuran i is formulated for use in the delicate skin around the eye area. Rejuran s is formulated with a focus on scarring and textural irregularities. Rejuran HB+ combines polynucleotides with hyaluronic acid, and may be discussed in relation to dehydrated skin or those with a lower tolerance for discomfort during treatment.
Which variant may be appropriate for you is a clinical decision. Speaking with a qualified practitioner is an appropriate starting point.
Rejuran i and Rejuran s share the same polynucleotide foundation but differ in their formulation and intended application. Rejuran i is formulated for use in the periorbital region, the delicate skin surrounding the eyes, where a lighter formulation is generally used to suit the sensitivity and thinness of that tissue.
Rejuran s is formulated with a focus on scarring and textural irregularities, often discussed in relation to acne scarring. Its concentration is intended to support the skin’s natural repair processes in skin that has been structurally affected rather than addressing general skin quality concerns.
A consultation with a qualified medical professional is the appropriate setting to determine which variant may be relevant to your specific concerns.
You cannot determine this through research alone. Which Rejuran variant may be appropriate depends on a range of individual factors, including the treatment area, the specific skin concerns involved, skin condition, and overall health profile.
According to the Australian Commission on Safety and Quality in Health Care, informed consent and thorough clinical assessment are fundamental to any cosmetic procedure. A qualified medical professional assesses these factors during a consultation and recommends a treatment plan based on individual circumstances rather than a general preference.
Combining Rejuran variants is something that may be discussed in a clinical context, depending on the individual’s concerns and skin profile. For example, a full face treatment using Rejuran Healer or HB+ may be considered alongside Rejuran i for the under-eye area as a complementary focus within the same treatment plan.
Whether combining variants is appropriate depends entirely on individual clinical assessment. It is not a decision that should be based on general information or assumptions. It is not a decision that should be based on general information or assumptions about Rejuran benefits.
A consultation with a qualified practitioner is the appropriate setting to explore whether a combined approach may be relevant to individual concerns and circumstances.
PDRN, or polydeoxyribonucleotide, and polynucleotides are closely related compounds that are often used interchangeably in discussions about bio-regenerative skin treatments. The distinction generally relates to their molecular size and the way they are processed. PDRN refers specifically to shorter chain DNA fragments, while polynucleotides encompass a broader range of chain lengths.
Rejuran is a polynucleotide based treatment developed in South Korea, and its formulation is informed by clinical research that has developed around this specific category of bio-regenerative compounds. As research into bio-regenerative compounds continues to develop, understanding the distinction between PDRN and polynucleotides is increasingly considered relevant in cosmetic medicine.
According to the University of Melbourne’s research into cellular repair, the science underpinning these treatments is an evolving field. A consultation with a qualified practitioner is an appropriate starting point to understand how these treatments may apply to individual skin circumstances.
